CK1-IN-4

• UNSPSC Description:

  CK1-IN-4 (Compound 59) is an inhibitor for casein kinase CK1δ with IC50 of 2.74 μM. CK1-IN-4 exhibits neuroprotective effect in Ethacrynic acid (HY-B1640)-treated SH-SY5Y cells[1].

• Target Antigen:

  Casein Kinase

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Stem Cell/Wnt

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ck1-in-4.html

• Smiles:

  NC1=NC(NCC2=CC=CC(OC)=C2)=NC3=NC(C4=CC=CS4)=NN31

• Molecular Weight:

  353.40

• References & Citations:

  [1]Grieco I, et al., 7-Amino-[1,2,4]triazolo[1,5-a][1,3,5]triazines as CK1δ inhibitors: Exploring substitutions at the 2 and 5-positions. Bioorg Chem. 2024 Jul 17;151:107659.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported