Products for Research Use Only
RegisterLogin

CK1δ-IN-9

CAT: 0804-HY-171292Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-171292Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CK1δ-IN-9 (Compound 8) is the inhibitor for casein kinase 1 that inhibits CK1δ with IC50 of 1.4 nM. CK1δ-IN-9 inhibits p38α and p38β with IC50 of 0.25 μM and 0.78 μM. CK1δ-IN-9 exhibits pharmacokinetic characteristics with a good oral bioavailability (70%) and a moderate clearance[1].
CAS Number
3057263-82-5
UNSPSC
12352005
Target
Casein Kinase; p38 MAPK
Related Pathways
Cell Cycle/DNA Damage; MAPK/ERK Pathway; Stem Cell/Wnt
Field of Research
Others
Smiles
FC1=CC=C(C2=NN(C)C=C2C3=C4C=NNC4=NC=C3)C=C1
Molecular Formula
C16H12FN5
Molecular Weight
293.30
References & Citations
[1]McCarver S, et al., Structure-Based Optimization of Selective and Brain Penetrant CK1δ Inhibitors for the Treatment of Circadian Disruptions. ACS Med Chem Lett. 2024 Mar 7;15 (4) :486-492.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK1; p38α; p38β

Related Products

CatalogName
HY-170860CK1δ/CK1ε liagnd-1
HY-128433-01CK1-IN-3
HY-171298CK1δ-IN-10
HY-169719CK1δ-IN-6
HY-W842364-01CK1δ-IN-3
HY-162756CK1-IN-4
HY-153866-01CK1-IN-2
HY-169556CK1δ-IN-7
HY-169713CK1δ-IN-5
HY-W840382-01CK1δ-IN-8

Alternative Products

CatalogName
T205445-01CK1δ-IN-9
GTR19249571-01CK1δ/CK1ε liagnd-1
GWB-59A291CK1
BA3747-1CK1-IN-2
BA3748-25CK1-IN-3
BA3738-25CK1-IN-1
T205270-01CK1δ-IN-5
MBS3605875CK1-IN-3c
CST 12448SCK1ε Antibody
CST 2655SCK1 Antibody

Popular Products