Calcifediol-d3

Calcifediol-d3

• CAS Number: 140710-94-7
• UNSPSC Description: Calcifediol-d3 is a deuterium labeled Calcifediol. Calcifediol, is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels[1][2][3].
• Target Antigen: Endogenous Metabolite; VD/VDR
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
• Field of Research: Metabolic Disease
• Purity: 99.06
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)(O)C)([H])/C(CCC1)=C/C([2H])=C3\C(CC[C@@H](C3)O)=C([2H])/[2H]
• Molecular Weight: 403.66
• References & Citations: [1]Castoldi A, et al. Calcifediol-loaded liposomes for local treatment of pulmonary bacterial infections. Eur J Pharm Biopharm. 2016 Nov 22.|[2]Wei Zheng, et al. Vitamin D-induced vitamin D receptor expression induces tamoxifen sensitivity in MCF-7 stem cells via suppression of Wnt/β-catenin signaling. Biosci Rep. 2018 Dec 7;38(6):BSR20180595.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light, stored under nitrogen)
• Clinical Information: No Development Reported