Calcifediol-d6

• Description:

  Calcifediol-d6 is the deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR ligand[1][2].

• Product Name Alternative:

  25-hydroxy Vitamin D3-d6

• UNSPSC:

  12352211

• Hazard Statement:

  H301

• Target:

  Isotope-Labeled Compounds; VD/VDR

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Others; Vitamin D Related/Nuclear Receptor

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Purity:

  99.09

• Solubility:

  DMSO : ≥ 100mg/mL

• Smiles:

  O[C@@H](CCC/1=C)CC1=C\C=C2[C@@](CC[C@@H]3[C@@H](CCCC(C([2H])([2H])[2H])(C([2H])([2H])[2H])O)C)([H])[C@]3(C)CCC\2

• Molecular Formula:

  C27H38D6O2

• Molecular Weight:

  406.67

• Precautions:

  H301

• References & Citations:

  [1]Trifu V, et al. Cortexolone 17α-propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double-blind comparative study vs. placebo and tretinoin 0•05% cream. Br J Dermatol. 2011 Jul;165 (1) :177-83.|[2]Celasco G, et al. Biological profile of cortexolone 17alpha-propionate (CB-03-01), a new topical and peripherally selective androgen antagonist. Arzneimittelforschung. 2004;54 (12) :881-6.|[3]Trifu V, et al. Cortexolone 17-propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double-blind comparative study vs. placebo and tretinoin 005% cream. Br J Dermatol. 2011 Jul;165 (1) :177-83.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light, stored under nitrogen)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  [78782-98-6]