Enpp-1-IN-2

• UNSPSC Description:

  Enpp-1-IN-2 (Compound C) is a potent ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1) inhibitor with IC50 values of 0.26, 0.48 and 2.0 μM evaluated by means of TG-mAMP, pNP-TMP, and ATP assays, respectively. TG (Tokyo Green)-mAMP: a newly synthesized sensitive ENPP1 fluorescence probe[1].

• Target Antigen:

  Phosphodiesterase (PDE)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/enpp-1-in-2.html

• Smiles:

  CC1=NC2=NC=NN2C(N(C)C)=C1CC3=CC=CC(N)=C3

• Molecular Weight:

  282.34

• References & Citations:

  [1]Kawaguchi M, et al. Development of an ENPP1 Fluorescence Probe for Inhibitor Screening, Cellular Imaging, and Prognostic Assessment of Malignant Breast Cancer. J Med Chem. 2019 Oct 24;62(20):9254-9269.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  2378640-92-5