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MTK458

CAT: 1410-M36457-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1410-M36457-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MTK458 (EP-0035985) is an orally active and brain-permeable PINK1 activator that promotes pathological clearance of alpha-synuclein and reduces pUb in a PFF inoculation model.MTK458 induces pathological alpha-synuclein clearance by stimulating dimerization and stabilization of the PINK1/TOM complex.MTK458 may be used in Parkinson's disease research.
CAS Number
2499962-58-0
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
332.32
Molecular Formula
C17H15F3N4
Notes
Research use only, not for human use.
Receptor
PTEN

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