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(Rac) -MTK458

CAT: 0804-HY-152943ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-152943ASize:1 Each
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Description
(Rac) -MTK458 (compound 16) is an activator of mitophagy. EP-0035985 is the isomer of EP-0035985[1].
CAS Number
2499962-44-4
Product Name Alternative
(Rac) -EP-0035985
UNSPSC
12352005
Target
Mitophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rac-mtk458.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C1=CC2=C(NC3C4=C(CCC3)C=CC=C4)N=CN=C2N1)F
Molecular Formula
C17H15F3N4
Molecular Weight
332.32
References & Citations
[1]De Roulet D, et al. Preparation of purinamines and pyrrolopyrimidinamines, compositions and methods of using the same for treatment of neurodegenerative and mitochondrial disease. World Intellectual Property Organization, WO2020206363 A1 2020-10-08.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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