Products for Research Use Only
RegisterLogin

NLRP3/AIM2-IN-3

CAT: 1410-M35421-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M35421-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NLRP3/AIM2-IN-3 is a unique molecule that inhibits NLRP3 and AIM2 inflammasome activation in a species-specific manner. It has an IC50 value for cell lysis of 0.077 ± 0.008 μ M. NLRP3/AIM2-IN-3 is a potent inhibitor of NLRP3 and AIM2 inflammasome-dependent cell lysis with an IC50 value for cell lysis of 0.077 ± 0.008 μ M. NLRP3/AIM2-IN-3 inhibits LPS/nigericin NLRP3/AIM2-IN-3 inhibits LPS/nigericin-stimulated cell lysis in THP-1 macrophages with an IC50 value of 0.077 ± 0.008 μM. NLRP3/AIM2-IN-3 interferes with the interaction of NLRP3 or AIM2 with the bridging protein ASC, inhibiting oligomerization of ASC.
CAS Number
1787787-60-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
266.29
Molecular Formula
C16H14N2O2
Notes
Research use only, not for human use.
Receptor
NOD | AIM2

Related Products

CatalogName
M35414-01NLRP3/AIM2-IN-2
M35514-01NLRP3-IN-11
M35555-01NLRP3-IN-10
M27905-01NLRP3-IN-9
M36488-01NLRP3-IN-13
M37305NLRP3 agonist 1
M12542-01NLRP3 Inflammasome Inhibitor I
M32521-013,3-Binaringenin
M32716-013,3-Tetramethyleneglutarimide
M37341-013,3-Selenobisalanine

Alternative Products

CatalogName
A8997-5NLRP3/AIM2-IN-3
T60404-01NLRP3/AIM2-IN-2
HY-144220NLRP3/AIM2-IN-1
HY-176452NLRP3 agonist 3

Popular Products