NLRP3/AIM2-IN-1

NLRP3/AIM2-IN-1

• UNSPSC Description: NLRP3/AIM2-IN-1 is a thermal sepsis inhibitor with an IC 50 value of 3.136 ± 0.7667 μ M.
• Target Antigen: NOD-like Receptor (NLR)
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/nlrp3-aim2-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=CC=C(C=C1)CC(NC2=CC=CC(B(O)O)=C2)=O
• Molecular Weight: 285.10
• References & Citations: [1]Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported