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NLRP3/AIM2-IN-1

CAT: 0804-HY-144220Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144220Size:1 Each
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Description
NLRP3/AIM2-IN-1 is a thermal sepsis inhibitor with an IC 50 value of 3.136 ± 0.7667 μ M.
UNSPSC
12352005
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nlrp3-aim2-in-1.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C=C1)CC(NC2=CC=CC(B(O)O)=C2)=O
Molecular Formula
C15H16BNO4
Molecular Weight
285.10
References & Citations
[1]Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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