MI-3454

• Description :

  MI-3454 is an orally active, selective and potent inhibitor of Menin-MLL1 interaction that inhibits the proliferation and induces differentiation of acute leukemia cells with MLL1 translocation or NPM1 mutation.MI-3454 induces complete remission or regression of leukemia in a mouse model of leukemia with MLL1 rearrangement or NPM1 mutation through the down-regulation of key genes involved in leukemogenesis. complete remission or remission.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  636.73

• Molecular Formula :

  C32H35F3N8OS

• Notes :

  Research use only, not for human use.

• Receptor :

  Histone Methyltransferase

• CAS Number :

  2134169-43-8