Furin Human

Furin Human_x000D_ Catalog number: B2018876_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 Units_x000D_ Molecular Weight or Concentration: 57 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: Dibasic-processing enzyme, Furin convertase, PACE, Paired basic amino acid residue-cleaving enzyme_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Osman EEA, Rehemtulla A, Neamati N. Why All the Fury over Furin? J Med Chem. 2022 Feb 24;65(4):2747-2784._x000D_ 2: Romeu AR. Probable human origin of the SARS-CoV-2 polybasic furin cleavage motif BMC Genom Data. 2023 Nov 21;24(1):71._x000D_ 3: He Z, Khatib AM, Creemers JWM. The proprotein convertase furin in cancer: more than an oncogene Oncogene. 2022 Feb;41(9):1252-1262._x000D_ 4: Pacheco A, Issaian A, Davis J, Anderson N, Nemkov T, Paukovich N, Henen MA, Vögeli B, Sikela JM, Hansen K. Proteolytic activation of human-specific Olduvai domains by the furin protease Int J Biol Macromol. 2023 Apr 15;234:123041._x000D_ 5: Zhang Y, Gao X, Bai X, Yao S, Chang YZ, Gao G. The emerging role of furin in neurodegenerative and neuropsychiatric diseases Transl Neurodegener. 2022 Aug 23;11(1):39._x000D_ 6: Hoffmann M, Kleine-Weber H, Pöhlmann S. A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells Mol Cell. 2020 May 21;78(4):779-784.e5._x000D_ 7: Douglas LEJ, Reihill JA, Montgomery BM, Martin SL. Furin as a therapeutic target in cystic fibrosis airways disease Eur Respir Rev. 2023 May 3;32(168):220256._x000D_ 8: Marafie SK, Al-Mulla F. An Overview of the Role of Furin in Type 2 Diabetes Cells. 2023 Oct 5;12(19):2407._x000D_ 9: Jaaks P, Bernasconi M. The proprotein convertase furin in tumour progression Int J Cancer. 2017 Aug 15;141(4):654-663._x000D_ 10: Luo L, Jia W, Zhang Y, Guo Y, Zhu J, Li C. Proprotein Convertase Furin Regulates Melanogenesis via the Notch Signaling Pathway Discov Med. 2023 Apr 1;35(175):144-156. _x000D_ _x000D_ Products Related to Furin Human can be found at Proteins

Catalog Number: B2018876 (50 Units)

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