Human HMGB2 Human (mammalian cell expression)

• Description:

  Human HMGB2 Human (mammalian cell expression)_x000D_ Catalog number: B2018904_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 1 ug_x000D_ Molecular Weight or Concentration: ~47_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -20„ƒ_x000D_ Keywords: N/A_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Jing Y, Jiang X, Ji Q, Wu Z, Wang W, Liu Z, Guillen-Garcia P, Esteban CR, Reddy P, Horvath S, Li J, Geng L, Hu Q, Wang S, Belmonte JCI, Ren J, Zhang W, Qu J, Liu GH. Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation Cell Stem Cell. 2023 Nov 2;30(11):1452-1471.e10._x000D_ 2: Neubert EN, DeRogatis JM, Lewis SA, Viramontes KM, Ortega P, Henriquez ML, Buisson R, Messaoudi I, Tinoco R. HMGB2 regulates the differentiation and stemness of exhausted CD8(+) T cells during chronic viral infection and cancer Nat Commun. 2023 Sep 13;14(1):5631._x000D_ 3: Taniguchi N, Kawakami Y, Maruyama I, Lotz M. HMGB proteins and arthritis Hum Cell. 2018 Jan;31(1):1-9._x000D_ 4: Zhang LX, Gao J, Long X, Zhang PF, Yang X, Zhu SQ, Pei X, Qiu BQ, Chen SW, Lu F, Lin K, Xu JJ, Wu YB. The circular RNA circHMGB2 drives immunosuppression and anti-PD-1 resistance in lung adenocarcinomas and squamous cell carcinomas via the miR-181a-5p/CARM1 axis Mol Cancer. 2022 May 7;21(1):110._x000D_ 5: Huang Y, Liangpunsakul S, Rudraiah S, Ma J, Keshipeddy SK, Wright D, Costa A, Burgess D, Zhang Y, Huda N, Wang L, Yang Z. HMGB2 is a potential diagnostic marker and therapeutic target for liver fibrosis and cirrhosis Hepatol Commun. 2023 Nov 6;7(11):e0299._x000D_ 6: Taniguchi N, Caramés B, Hsu E, Cherqui S, Kawakami Y, Lotz M. Expression patterns and function of chromatin protein HMGB2 during mesenchymal stem cell differentiation J Biol Chem. 2011 Dec 2;286(48):41489-41498._x000D_ 7: Zhai Y, Qi Y, Long X, Dou Y, Liu D, Cheng G, Xiao J, Liu Z, Zhao Z. Elevated hsa-miR-590-3p expression down-regulates HMGB2 expression and contributes to the severity of IgA nephropathy J Cell Mol Med. 2019 Nov;23(11):7299-7309._x000D_ 8: Kučírek M, Bagherpoor AJ, JaroÅ¡ J, Hampl A, Å tros M. HMGB2 is a negative regulator of telomerase activity in human embryonic stem and progenitor cells FASEB J. 2019 Dec 1;33(12):14307-14324._x000D_ 9: Zheng X, Liu Z, Bin Y, Wang J, Rao X, Wu G, Dong X, Tong F. Ionizing radiation induces vascular smooth muscle cell senescence through activating NF-κB/CTCF/p16 pathway Biochim Biophys Acta Mol Basis Dis. 2024 Mar;1870(3):166994._x000D_ 10: Stros M, Polanská E, Struncová S, Pospísilová S. HMGB1 and HMGB2 proteins up-regulate cellular expression of human topoisomerase IIalpha Nucleic Acids Res. 2009 Apr;37(7):2070-86. _x000D_ _x000D_ Products Related to Human HMGB2 Human (mammalian cell expression) can be found at Proteins

• Short Description:

  Catalog Number: B2018904 (1 ug)_x000D_ HMGB2 (High Mobility Group Box 2) is a protein that is part of the high mobility group (HMG) family of proteins. It is involved in various cellular processes, including DNA binding, transcription regulation, and chromatin remodeling. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5