Fluorogenic Furin Substrate

CAT: 0952-B2012668Size: 5 mgDry Ice: NoHazardous: No
CAT#:0952-B2012668Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fluorogenic Furin Substrate_x000D_ Catalog number: B2012668_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 5 mg_x000D_ Molecular Weight or Concentration: 827.9 g/mol_x000D_ Supplied as: Lyophilized Powder_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -20°C_x000D_ Keywords: Furin Substrate, Fluorogenic_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Zhu J, Declercq J, Creemers JW, Chen C, Cui Y, Van de Ven WJ, Vermorken AJ. Limitations of inhibitory activities of polyphenols on furin-mediated substrate processing Curr Med Chem. 2012;19(21):3641-50._x000D_ 2: Angliker H, Neumann U, Molloy SS, Thomas G. Internally quenched fluorogenic substrate for furin Anal Biochem. 1995 Jan 1;224(1):409-12._x000D_ 3: Jean F, Basak A, DiMaio J, Seidah NG, Lazure C. An internally quenched fluorogenic substrate of prohormone convertase 1 and furin leads to a potent prohormone convertase inhibitor Biochem J. 1995 May 1;307 ( Pt 3)(Pt 3):689-95._x000D_ 4: Lam van TV, Ivanova T, Lindberg I, Böttcher-Friebertshäuser E, Steinmetzer T, Hardes K. Design, synthesis, and characterization of novel fluorogenic substrates of the proprotein convertases furin, PC1/3, PC2, PC5/6, and PC7 Anal Biochem. 2022 Oct 15;655:114836._x000D_ 5: Zaragoza-Huesca D, Martínez-Cortés C, Banegas-Luna AJ, Pérez-Garrido A, Vegara-Meseguer JM, Peñas-Martínez J, Rodenas MC, Espín S, Pérez-Sánchez H, Martínez-Martínez I. Identification of Kukoamine A, Zeaxanthin, and Clexane as New Furin Inhibitors Int J Mol Sci. 2022 Mar 3;23(5):2796._x000D_ 6: Tanikawa T, Hayashi T, Suzuki R, Kitamura M, Inoue Y. Inhibitory effect of honokiol on furin-like activity and SARS-CoV-2 infection J Tradit Complement Med. 2022 Jan;12(1):69-72._x000D_ 7: Fei H, Li Y, Wang LX, Luo MJ, Ling MH, Chi CW. Nonhistone protein purified from porcine kidney acts as a suicide substrate inhibitor on furin-like enzyme Acta Pharmacol Sin. 2000 Mar;21(3):265-70._x000D_ 8: Lazure C, Gauthier D, Jean F, Boudreault A, Seidah NG, Bennett HP, Hendy GN. In vitro cleavage of internally quenched fluorogenic human proparathyroid hormone and proparathyroid-related peptide substrates by furin. Generation of a potent inhibitor J Biol Chem. 1998 Apr 10;273(15):8572-80._x000D_ 9: Rozan L, Krysan DJ, Rockwell NC, Fuller RS. Plasticity of extended subsites facilitates divergent substrate recognition by Kex2 and furin J Biol Chem. 2004 Aug 20;279(34):35656-63._x000D_ 10: Lee MJ. Heparin inhibits activation of latent transforming growth factor-β1 Pharmacology. 2013;92(5-6):238-44. _x000D_ _x000D_ Products Related to Fluorogenic Furin Substrate can be found at Substrates
Short Description
Catalog Number: B2012668 (5 mg)
Weight
0.15
Length
2
Width
0.5
Height
0.5

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