TARC (CCL17)

• Description:

  TARC, a CC chemokine, is predominantly produced by dendritic cells in the thymus and signals through the CCR4 receptor. TARC is chemotactic towards T cells. Recombinant human TARC is an 8.0 kDa protein containing 71 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

• Synonyms:

  CCL17; TARC; ABCD-2; SCYA17; A-152E5.3

• NCBI Gene ID:

  6361

• UniProt:

  Q92583

• Accession Number:

  NP_002978.1

• Accession Number mRNA:

  NM_002987

• Chromosomal Location:

  16q13

• Reactivity:

  Human

• Cross Reactivity:

  Mouse, Human, Bacteria

• Sequence:

  ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity:

  Determined by its ability to chemoattract human T cells using a concentration range of 1.0-10.0 ng/ml.

• Length:

  71

• Form:

  Lyophilized

• Molecular Weight:

  8 kDa

• Host or Source:

  E. coli