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CCL-17 (TARC)

CAT: 0209-101-M260Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M260Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CCL17 is a novel CC chemokine identified using a signal sequence trap method. CCL17 cDNA encodes a highly basic 94 amino acid (aa) residue precursor protein with a 23 aa residue signal peptide that is cleaved to generate the 71 aa residue mature secreted protein. Among CC chemokine family members, CCL17 has approximately 24-29% amino acid sequence identity with RANTES, MIP1α, MIP1β, MCP1, MCP2, MCP3, and I309. The gene for human CCL17 has been mapped to chromosome 16q13 rather than chromosome 17 where the genes for many human CC chemokines are clustered. CCL17 is constitutively expressed in thymus, and at a lower level in lung, colon, and small intestine. CCL17 is also transiently expressed in stimulated peripheral blood mononuclear cells. Recombinant CCL17 has been shown to be chemotactic for T cell lines but not monocytes or neutrophils. CCL17 was identified to be a specific functional ligand for CCR4, a receptor that is selectively expressed on T cells.
Synonyms
CCL17; TARC; ABCD-2; SCYA17; A-152E5.3
NCBI Gene ID
6361
UniProt
Q92583
Accession Number
NP_116741
Accession Number mRNA
NM_002987
Chromosomal Location
16q13
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human CCL-17
Clone
(#6J30)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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Alternative Products

CatalogName
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GTR18090668Mouse Monoclonal human CCL-17 (TARC) Antibody
hAP-0141AMouse Monoclonal anti-human CCL-17 (TARC)
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GTR18090039Rat Monoclonal mouse CCL-17 (TARC) Antibody
216189CCL-17 (TARC, Chemokine C-C Motif Ligand 17)
220304TARC, Recombinant, Human (C-C Motif Chemokine 17, Small-Inducible Cytokine A17, Thymus and Activation-Regulated Chemokine, CC Chemokine TARC, ABCD-2, CCL17, CCL-17, SCYA17, TARC, A-152E53, MGC138271, MGC138273) discontinued
MBS8532899-01C-C motif chemokine 17/CCL17/TARC
500480TARC, Recombinant, Human (CC Chemokine TARC, Small-Inducible Cytokine A17, C-C Motif Chemokine 17, Chemokine 17, CCL17, ABCD-2, SCYA17, TARC, Thymus and Activation-Regulated Chemokine, CCL17) discontinued
142475Thymus Activation Regulated Chemokine (TARC, ABCD-2, CCL17, SCYA17, TARC, Small Inducible Cytokine Subfamily A (Cys-Cys) Member 17)

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