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CCL17 / TARC Protein

CAT: 0209-M60-010-L1000Size: 1000 µgDry Ice: YesHazardous: No
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CAT#:0209-M60-010-L1000Size:1000 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine (TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the chemokine receptor CCR4.
Synonyms
Abcd-2 Protein; Ccl17 Protein; Scya17 Protein; Scya17l Protein; Tarc Protein
Accession Number
AAD56601.1
Reactivity
Mouse
Cross Reactivity
Mouse
Assay Protocol
See Datasheet send with the product
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 95 % as determined by SDS-PAGE
Bioactivity
Data not available
Length
73
Form
Lyophilized or frozen liquid
Buffer
20 mM Tris, 500 mM NaCl, 10 % Glycerol, pH 7.4
Reconstitution
See Datasheet send with the product
Molecular Weight
8.2 kDa
Storage Conditions
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Host or Source
Insect cells

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Alternative Products

CatalogName
UA040321-01CCL17/TARC Protein, Human
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CD00208Recombinant Mouse TARC/CCL17 protein
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TP726825TARC (CCL17) Human Recombinant Protein
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