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IL-8 (72aa) (CXCL8)

CAT: 0209-100-046-L50Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-100-046-L50Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant human IL-8 (monocyte-derived) is an 8.4 kDa protein containing 72 amino acid residues.
Synonyms
IL8; NAF; GCP1; LECT; LUCT; NAP1; CXCL8; GCP-1; LYNAP; MDNCF; MONAP; NAP-1
NCBI Gene ID
3576
UniProt
P10145
Accession Number
NP_000575.1
Accession Number mRNA
NM_000584.3
Chromosomal Location
4q13-q21
Reactivity
Human
Cross Reactivity
Monkey, Mouse, Rat, Human, Bacteria
Sequence
SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS
Assay Protocol
Centrifuge the vial prior for opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml.
Length
72
Form
Lyophilized
Reconstitution
Water
Molecular Weight
8.4 kDa
Storage Conditions
The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.
Host or Source
E. coli

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