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CXCL8 (IL-8)

CAT: 0209-101-M358Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M358Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CXCL8 was originally discovered and purified as a neutrophil chemotactic and activating factor. It was also referred to as neutrophil chemotactic factor (NCF), neutrophil activating protein (NAP), monocytederived neutrophil chemotactic factor (MDNCF), T lymphocyte chemotactic factor (TCF), granulocyte chemotactic protein (GCP) and leukocyte adhesion inhibitor (LAI) . Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, chondrocytes, and various tumor cell lines, can produce CXCL8 in response to a wide variety of proinflammatory stimuli such as exposure to IL-1, TNF, LPS, and viruses. CXCL8 is a member of the alpha (CXC) subfamily of chemokines, which also includes platelet factor-4, GRO, and IP10.
Synonyms
IL8; NAF; GCP1; LECT; LUCT; NAP1; CXCL8; GCP-1; LYNAP; MDNCF; MONAP; NAP-1
NCBI Gene ID
3576
UniProt
P10145
Accession Number
NP_000575.1
Accession Number mRNA
NM_000584.3
Chromosomal Location
4q13-q21
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant CXCL8 (IL-8)
Clone
(#7F11)
Applications
WB, IHC, FC, N
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Bioactivity
IHC (frozen) 1:20-100; FC 1:50-200; WB 1:500-1000; Neutralization of CXCL8 mediated bioreactivity
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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