Products for Research Use Only
RegisterLogin

CD80 / B7-1 Protein

CAT: 0209-600-060-L100Size: 100 µgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0209-600-060-L100Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. As costimulatory ligands, B7-1 which exists predominantly as dimer and the related protein B7-2, interact with the costimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus constitute one of the dominant pathways that regulate T cell activation and tolerance, cytokine production, and the generation of CTL. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas.
Synonyms
B7 Protein; B71 Protein; Cd28l Protein; Cd80 Protein; Ly-53 Protein; Ly53 Protein; MIC17 Protein; TSA1 Protein
Accession Number
NP_005182.1
Reactivity
Human
Cross Reactivity
Human
Assay Protocol
See Datasheet send with the product
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 95 % as determined by SDS-PAGE
Bioactivity
Data not available
Length
214
Form
Lyophilized
Buffer
PBS, pH 7.4
Reconstitution
See Datasheet
Molecular Weight
45 kDa (glycosylated)
Storage Conditions
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Host or Source
HEK 293 cells

Related Products

CatalogName
101-M315CD80 (B7-1)
103-M144CD80 (B7-1)
M60-055-L100CD80 / B7-1 / CD28LG Protein (His Tag)
M60-055-L1000CD80 / B7-1 / CD28LG Protein (His Tag)
M60-057-L100CD86 / B7-2 Protein (His Tag)
600-062-L100CD86 / B7-2 Protein (His Tag)
M60-056_L1000CD86 / B7-2 Protein (hFc Tag)
M60-056_L100CD86 / B7-2 Protein (hFc Tag)
R60-007-L100CD86 / B7-2 Protein (His Tag)
600-062-L1000CD86 / B7-2 Protein (His Tag)

Alternative Products

CatalogName
GTR18985808-01Human B7-1/CD80 protein
P514183CD80/B7-1 Protein (Human)
GTR18985806-01Mouse B7-1/CD80 protein
11-527B7-1 / CD80 Recombinant Protein
MBS9144137-01Recombinant Mouse B7-1/CD80 Protein
PX-P4040-50Human CD80, B7-1 recombinant protein
PPT-16431Mouse CD80/B7-1 Recombinant Protein
NBP2-48954PEPB7-1/CD80 Recombinant Protein Antigen
RM808020Anti-Mouse CD80 (B7 1 Protein)
RP00739Recombinant Cynomolgus B7-1/CD80 Protein

Popular Products