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IFI16 (CT) Peptide

CAT: 0223-9641PSize: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-9641PSize:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IFI16 Antibody: IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer. Increased expression of IFI16 predicts adverse prognosis in multiple myeloma. IFI16 isoforms with cytoplasmic and nuclear locations play differential roles in recognizing invaded DNA viruses. IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection. Nuclear sensor IFI16 inhibits the function of Hepatitis B virus covalently closed circular DNA by integrating innate immune activation and epigenetic suppression.
NCBI Gene ID
3428
Swiss Prot
Q16666
Accession Number
Q16666.3
Type
Peptides
Concentration
200 ug/mL
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Shipping Conditions
Blue Ice
Storage Conditions
Store ULBP1 peptide at -20˚ C, stable for one year.
Applications Notes
IFI16 (CT) Peptide is used for blocking the activity of IFI16 (CT) Antibody.
NCBI Official Name
Interferon gamma inducible protein 16
NCBI Organism
Homo sapiens
Background Reference 01
Ka et al. Cell Rep. 2021; 37 (12) :110138
Background Reference 02
Huang et al. Pharmacogenomics J. 2021; 21 (4) :520-532
Background Reference 03
Li et al. J Immunol. 2021; 207 (11) :2699-2709
Background Reference 04
Jiang et al. Nat Microbiol. 2021; 6 (7) :932-945
Background Reference 05
Yang et al. Hepatology 2020; 71 (4) :1154-1169
Other Product Names
IFI16 Antibody: Gamma-interferon-inducible protein 16, Ifi-16, Interferon-inducible myeloid differentiation transcriptional activator, IFNGIP1
Tested Applications
Blocking
Species
Human
Protein ID
118572657
Physical Properties
Liquid

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