IFI16 (CT) Peptide

• Background:

  IFI16 Antibody: IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer. Increased expression of IFI16 predicts adverse prognosis in multiple myeloma. IFI16 isoforms with cytoplasmic and nuclear locations play differential roles in recognizing invaded DNA viruses. IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection. Nuclear sensor IFI16 inhibits the function of Hepatitis B virus covalently closed circular DNA by integrating innate immune activation and epigenetic suppression.

• NCBI Gene ID:

  3428

• Swiss Prot:

  Q16666

• Accession Number:

  Q16666.3

• Type:

  Peptides

• Concentration:

  200 ug/mL

• Buffer:

  PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store ULBP1 peptide at -20˚ C, stable for one year.

• Applications Notes:

  IFI16 (CT) Peptide is used for blocking the activity of IFI16 (CT) Antibody.

• NCBI Official Name:

  Interferon gamma inducible protein 16

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ka et al. Cell Rep. 2021; 37 (12) :110138

• Background Reference 02:

  Huang et al. Pharmacogenomics J. 2021; 21 (4) :520-532

• Background Reference 03:

  Li et al. J Immunol. 2021; 207 (11) :2699-2709

• Background Reference 04:

  Jiang et al. Nat Microbiol. 2021; 6 (7) :932-945

• Background Reference 05:

  Yang et al. Hepatology 2020; 71 (4) :1154-1169

• Other Product Names:

  IFI16 Antibody: Gamma-interferon-inducible protein 16, Ifi-16, Interferon-inducible myeloid differentiation transcriptional activator, IFNGIP1

• Tested Applications:

  Blocking

• Species:

  Human

• Protein ID:

  118572657

• Physical Properties:

  Liquid