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POLRMT (CT) Peptide

CAT: 0223-9561PSize: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-9561PSize:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
POLRMT Antibody: This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. TFB2M and POLRMT are essential for mammalian mitochondrial DNA replication. POLRMT mutations impair mitochondrial transcription causing neurological disease. Knock-down of MRPL12 by RNA interference results in instability of POLRMT.
NCBI Gene ID
5442
Swiss Prot
O0411
Accession Number
O0411.2
Type
Peptides
Concentration
200 ug/mL
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Shipping Conditions
Blue Ice
Storage Conditions
Store ULBP1 peptide at -20˚ C, stable for one year.
Applications Notes
POLRMT (CT) Peptide is used for blocking the activity of POLRMT (CT) Antibody.
NCBI Official Name
RNA polymerase mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Inatomi et al. Biochim Biophys Acta Mol Cell Res. 2022; 1869 (1) ; 119167
Background Reference 02
Olahova et al. Nat Commun. 2021; 12 (1) :1135
Background Reference 03
Nouws et al. J Biol Chem 2016; 291 (2) :989-997
Other Product Names
DNA-directed RNA polymerase, mitochondrial, MtRPOL, POLRMT Isoforms
Tested Applications
Blocking
Species
Human
Protein ID
50403691
Physical Properties
Liquid