PGAM5 (CT) Peptide

• Background:

  PGAM5 Antibody: PGAM5 is a central mediator for programmed necrosis induced by TNF and may be a regulator of mitochondrial dynamics. It displays phosphatase activity for serine/threonine residues, dephosphorylates and activates MAP3K5 kinase. It has apparently no phosphoglycerate mutase activity and is a substrate for a KEAP1-dependent ubiquitin ligase complex. It is also contributes to the repression of NFE2L2-dependent gene expression

• NCBI Gene ID:

  192111

• Swiss Prot:

  Q96HS1

• Accession Number:

  Q96HS1

• Type:

  Peptides

• Concentration:

  200 ug/mL

• Buffer:

  PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store PGAM5 (CT) Peptide at -20˚ C, stable for one year.

• Applications Notes:

  PGAM5 (CT) Peptideis used for blocking the activity of thePGAM5 (CT) Antibody

• NCBI Official Name:

  PGAM family member 5, mitochondrial serine/threonine protein phosphatase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lo S. et al. Exp. Cell Res. 2018; 314 (8) : 1789-1803

• Background Reference 02:

  Takeda et al. PNAS 2009; 106 (30) : 12301-12305

• Background Reference 03:

  Want et al. Cell 2012; 148 (1-2) ; 228-243

• Other Product Names:

  Serine/threonine-protein phosphatase PGAM5 mitochondrial, Bcl-XL-binding protein v68, Phosphoglycerate mutase family member 5

• Tested Applications:

  Blocking

• Species:

  Human

• Protein ID:

  150417955

• Physical Properties:

  Liquid