GDF-3 Recombinant Protein

• Background:

  GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes. Recombinant human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains.

• NCBI Gene ID:

  9573

• Swiss Prot:

  Q9NR23

• Accession Number:

  NP_065685.1

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Growth Factors, Signal Transduction

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized GDF-3 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted GDF-3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing GDF-3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Growth differentiation factor 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  KFS3, MCOP7, MCOPCB6GDF-3

• Species:

  Human

• Protein ID:

  10190670

• Physical Properties:

  Lyophilized