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GDF-3 Recombinant Protein

CAT: 0223-40-220-01Size: 0.005 mgDry Ice: NoHazardous: No
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CAT#:0223-40-220-01Size:0.005 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes. Recombinant human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains.
NCBI Gene ID
9573
Swiss Prot
Q9NR23
Accession Number
NP_065685.1
Type
Recombinant Proteins
Source
E. coli
Field of Research
Growth Factors, Signal Transduction
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized GDF-3 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted GDF-3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing GDF-3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Growth differentiation factor 3
NCBI Organism
Homo sapiens
Other Product Names
KFS3, MCOP7, MCOPCB6GDF-3
Species
Human
Protein ID
10190670
Physical Properties
Lyophilized

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