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GDF-2 Recombinant Protein

CAT: 0223-40-517-01Size: 0.002 mgDry Ice: NoHazardous: No
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CAT#:0223-40-517-01Size:0.002 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GDF-2 belongs to the TGF-B cytokine family whose members play an important role during prenatal development and postnatal growth, remodeling and maintenance of a variety of tissues and organs. GDF-2 is expressed mainly in nonparenchymal cells of the liver, but is also found in other various cells and tissues. GDF-2 can signal through the ALK1 receptor and has been implicated in a number of physiologic events. These include regulation of the hepatic reticuloendothelial system, glucose homeostasis, and iron homeostasis, as well as the inhibition of angiogenesis. Recombinant human GDF-2 is a 24.1 kDa disulfide linked homodimeric protein consisting of two 110 amino acid polypeptide chains.
NCBI Gene ID
2658
Swiss Prot
Q9UK05
Accession Number
NP_057288.1
Type
Recombinant Proteins
Source
CHO cells
Field of Research
Growth Factors, Signal Transduction
Purity
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized GDF-2 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted GDF-2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing GDF-2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Growth differentiation factor 2
NCBI Organism
Homo sapiens
Other Product Names
BMP9, HHT5, BMP-9, BMP9, Bone morphogenetic protein 9, GDF-2
Species
Human
Protein ID
7705308
Physical Properties
Lyophilized

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