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GDF-8 Recombinant Protein

CAT: 0223-92-443Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-443Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Growth/differentiation factor 8 (Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.
CAS Number
9000-83-3
NCBI Gene ID
2660
Swiss Prot
O14793
Accession Number
O14793
Tag
Tag Free
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Growth Factors, Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
13 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Myostatin
NCBI Organism
Homo sapiens
Other Product Names
Growth/differentiation factor 8, GDF-8, Myostatin, Mstn, Gdf8
Species
Human
Physical Properties
Lyophilized

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