GDF-8 Recombinant Protein

• Background:

  Growth/differentiation factor 8 (Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.

• NCBI Gene ID:

  2660

• Swiss Prot:

  O14793

• Accession Number:

  O14793

• Tag:

  Tag Free

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Growth Factors, Signal Transduction

• Buffer:

  Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  13 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Myostatin

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Growth/differentiation factor 8, GDF-8, Myostatin, Mstn, Gdf8

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3