Synaptophysin Antibody

• Background:

  Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity

• NCBI Gene ID:

  6855

• Swiss Prot:

  P08247

• Accession Number:

  NP_003170.1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Synaptophysin antibody was raised against a peptide sequence around aa.305~309 (A-P-T-S-F) derived from Human Synaptophysin.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  38 kDa

• Specificity:

  This antibody detects endogenous levels of total Synaptophysin protein.

• Applications Notes:

  Western Blot: 1:500~1:1000

• Symbol:

  SYP

• NCBI Official Name:

  Synaptophysin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  "Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex. "Ito H., Atsuzawa K., Sudo K., Di Stefano P., Iwamoto I., Morishita R., Takei S., Semba R., Defilippi P., Asano T., Usuda N., Nagata K. J. Neurochem. 107:61-72 (2008) "A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation. "Tarpey P. S., Smith R., Pleasance E., et al. Nat. Genet. 41:535-543 (2009)

• Other Product Names:

  MRX96, MRXSYP, GP3A

• Tested Applications:

  WB

• Protein ID:

  27764867

• Physical Properties:

  Liquid