Synaptophysin Antibody

• Background :

  Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity

• NCBI Gene ID :

  6855

• Swiss Prot :

  P08247

• Accession Number :

  NP_003170.1

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Synaptophysin antibody was raised against a peptide sequence around aa.305~309 (A-P-T-S-F) derived from Human Synaptophysin.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience

• Purification :

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration :

  1 mg/mL

• Buffer :

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight :

  38 kDa

• Specificity :

  This antibody detects endogenous levels of total Synaptophysin protein.

• Applications Notes :

  Western Blot: 1:500~1:1000

• Symbol :

  SYP

• NCBI Official Name :

  Synaptophysin

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  "Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex. "Ito H., Atsuzawa K., Sudo K., Di Stefano P., Iwamoto I., Morishita R., Takei S., Semba R., Defilippi P., Asano T., Usuda N., Nagata K. J. Neurochem. 107:61-72 (2008) "A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation. "Tarpey P. S., Smith R., Pleasance E., et al. Nat. Genet. 41:535-543 (2009)

• Other Product Names :

  MRX96, MRXSYP, GP3A

• Tested Applications :

  WB

• Protein ID :

  27764867

• Physical Properties :

  Liquid