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STAT3 (Ab 705) Antibody

CAT: 0223-79-286Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-286Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transcription factor that binds to the interleukin-6 (IL-6) -responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.
NCBI Gene ID
6774
Swiss Prot
P40763
Accession Number
NP_003141.2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
STAT3 (Ab-705) antibody was raised against a peptide sequence around aa.703~707 (A-P-Y-L-K) derived from Human STAT3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
88 kDa
Specificity
This antibody detects endogenous level of total STAT3 protein.
Applications Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: IF:1:100~1:200
Symbol
STAT3
NCBI Official Name
Signal transducer and activator of transcription 3 (acute-phase response factor)
NCBI Organism
Homo sapiens
Background Reference 01
Heim M H, (1999) J Recept Signal Transduct Res. 19: 75-120. Takeda K, et al. (1997) Proc Natl Acad Sci USA. 94: 3801-3804. Catlett-Falcone R, et al. (1999) Immunity. 10: 105-115. Garcia R, et al. (1998) J Biomed Sci. 5: 79-85. Bromberg J F, et al. (1999) Cell. 98: 295-303.
Other Product Names
APRF, HIES, BSP1, MADH1, MADR1, APRF, Acute-phase response factor
Tested Applications
WB, IHC, IF
Protein ID
21618338
Physical Properties
Liquid

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