DUSP6 Antibody

• Background :

  The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This protein product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm.

• NCBI Gene ID :

  1848

• Swiss Prot :

  Q16828

• Accession Number :

  NP_001937.1

• Host :

  Chicken

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  135-280

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  Immunoaffinity Purified

• Concentration :

  1 mg/mL

• Buffer :

  Phosphate-Buffered Saline. No preservatives added.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  DUSP6 antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  15.1 kDa (calculated)

• Applications Notes :

  Dual specificity phosphatase 6 antibody can be used for the detection of Dual specificity phosphatase 6 by Western Blot.

• Symbol :

  DUSP6

• NCBI Official Name :

  Dual specificity phosphatase 6

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  MKP3, PYST1, Dual specificity protein phosphatase 6, Dual specificity protein phosphatase PYST1, MAP kinase phosphatase 3, HH19, MKP3, Dual specificity phosphatase 6

• Tested Applications :

  WB

• Protein ID :

  4503419

• Physical Properties :

  Liquid