DUSP9 Antibody

CAT: 0223-57-334Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-334Size:400 µL
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Background
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus. [provided by RefSeq].
NCBI Gene ID
1852
Swiss Prot
Q99956
Accession Number
Q99956
Host
Rabbit
Reactivity
Human
Immunogen
This DUSP9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-329 amino acids from the C-terminal region of human DUSP9.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Symbol
DUSP9
NCBI Official Name
Dual specificity protein phosphatase 9
NCBI Organism
Homo sapiens
Background Reference 01
Voight, B.F., et al. Nat. Genet. 42 (7) :579-589 (2010)
Background Reference 02
Liu, Y., et al. Cancer Res. 67 (22) :10711-10719 (2007)
Background Reference 03
Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)
Background Reference 04
Muda, M., et al. J. Biol. Chem. 272 (8) :5141-5151 (1997)
Other Product Names
Dual specificity protein phosphatase 9, Mitogen-activated protein kinase phosphatase 4, MAP kinase phosphatase 4, MKP-4, DUSP9, MKP4
Tested Applications
WB, IHC-P
Protein ID
3913541
Physical Properties
Liquid

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