NEDD4 Antibody

• Background:

  Nedd4 is one of a group of mouse genes that show developmentally regulated expression in mouse embryonic brain. Nedd4 is expressed in various other embryonic tissues and persists in most adult tissues.

• NCBI Gene ID:

  4734

• Swiss Prot:

  P46934

• Accession Number:

  P46934

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This NEDD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1288-1319 amino acids from the C-terminal region of human NEDD4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  149 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  NEDD4

• NCBI Official Name:

  E3 ubiquitin-protein ligase NEDD4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lin, Q., et al. Mol. Cell. Biol. 30 (6) :1541-1554 (2010)

• Background Reference 02:

  Crowther-Swanepoel, D., et al. Nat. Genet. 42 (2) :132-136 (2010)

• Background Reference 03:

  Edwin, F., et al. J. Biol. Chem. 285 (1) :255-264 (2010)

• Background Reference 04:

  Guo, Y.Y., et al. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 31 (6) :679-685 (2009)

• Other Product Names:

  E3 ubiquitin-protein ligase NEDD4, 632-, Cell proliferation-inducing gene 53 protein, Neural precursor cell expressed developmentally down-regulated protein 4, NEDD-4, NEDD4, KIAA0093, NEDD4-1

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  313104311

• Physical Properties:

  Liquid