NEDD9 Antibody

• Background:

  The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  4739

• Swiss Prot:

  Q14511

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 60-174 of human NEDD9 (NP_892011.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 115kDa

• Fragment:

  IgG

• Symbol:

  NEDD9

• NCBI Official Name:

  Neural precursor cell expressed, developmentally down-regulated 9

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  NEDD9, CAS-L, CASL, HEF1, dJ49G10.2, dJ761I2.1, CAS2, CASS2

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid