NEDD9 Antibody

• Background:

  Variation in NEDD9 is associated wih susceptibility to late-onset Alzheimer and Parkinson diseases. Changes in expression of the scaffold protein HEF1/CAS-L/NEDD9 were found to be a potent prometastatic stimulus in melanoma and other cancers.

• NCBI Gene ID:

  4739

• Swiss Prot:

  Q14511

• Accession Number:

  NP_006394

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NEDD9.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Cancer, Signal Transduction

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  721_B Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NEDD9 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  93 kDa

• Applications Notes:

  NEDD9 antibody can be used for detection of NEDD9 by ELISA at 1:62500. NEDD9 antibody can be used for detection of NEDD9 by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  NEDD9

• NCBI Official Name:

  Neural precursor cell expressed, developmentally down-regulated 9

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Li, Y., (2008) Hum. Mol. Genet. 17 (5), 759-767.

• Other Product Names:

  NEDD9, CAS-L, CASL, HEF1, dJ49G10.2, dJ761I2.1, CAS2, CASS2

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  5453680

• Physical Properties:

  Liquid