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CACNA2D3 Antibody

CAT: 0223-64-087Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-64-087Size:400 µL
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Background
CACNA2D3 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.
NCBI Gene ID
55799
Swiss Prot
Q8IZS8
Accession Number
Q8IZS8
Host
Rabbit
Reactivity
Human
Immunogen
This CACNA2D3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1026-1053 amino acids from the C-terminal region of human CACNA2D3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
123 kDa
Fragment
Rabbit Ig
Symbol
CACNA2D3
NCBI Official Name
Voltage-dependent calcium channel subunit alpha-2/delta-3
NCBI Organism
Homo sapiens
Background Reference 01
Trynka, G., et al. Gut 58 (8) :1078-1083 (2009)
Background Reference 02
Wanajo, A., et al. Gastroenterology 135 (2) :580-590 (2008)
Background Reference 03
Uhl, G.R., et al. Arch. Gen. Psychiatry 65 (6) :683-693 (2008)
Background Reference 04
Abo-Dalo, B., et al. Am. J. Med. Genet.143A (22), 2668-2674 (2007)
Other Product Names
Voltage-dependent calcium channel subunit alpha-2/delta-3, Voltage-gated calcium channel subunit alpha-2/delta-3, Voltage-dependent calcium channel subunit alpha-2-3, Voltage-dependent calcium channel subunit delta-3, CACNA2D3
Tested Applications
WB, Flow
Protein ID
74723683
Physical Properties
Liquid

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