DKK1 Antibody

CAT: 0223-64-019Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-64-019Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DKK1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
NCBI Gene ID
22943
Swiss Prot
O94907
Accession Number
O94907
Host
Rabbit
Reactivity
Human
Immunogen
This DKK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-84 amino acids from the N-terminal region of human DKK1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
29 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DKK1
NCBI Official Name
Dickkopf-related protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Piters, E., et al. Calcif. Tissue Int. 86 (4) :271-281 (2010)
Background Reference 02
Bourhis, E., et al. J. Biol. Chem. 285 (12) :9172-9179 (2010)
Other Product Names
Dickkopf-related protein 1, Dickkopf-1, Dkk-1, hDkk-1, SK, DKK1
Tested Applications
WB
Physical Properties
Liquid

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