DKK4 Antibody

• Background:

  This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. Activity of this protein is modulated by binding to the Wnt co-receptor and the co-factor kremen 2.

• NCBI Gene ID:

  27121

• Swiss Prot:

  Q9UBT3

• Accession Number:

  Q9UBT3

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This DKK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-189 amino acids from the C-terminal region of human DKK4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  25 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  DKK4

• NCBI Official Name:

  Dickkopf-related protein 4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hosgood, H.D. III, et al. Occup Environ Med 66 (12) :848-853 (2009)

• Background Reference 02:

  Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)

• Background Reference 03:

  Hirata, H., et al. Cancer 115 (19) :4488-4503 (2009)

• Background Reference 04:

  Matsui, A., et al. Cancer Sci. 100 (10) :1923-1930 (2009)

• Other Product Names:

  Dickkopf-related protein 4, Dickkopf-4, Dkk-4, hDkk-4, Dickkopf-related protein 4 short form, DKK4

• Tested Applications:

  WB

• Protein ID:

  13124092

• Physical Properties:

  Liquid