ING5 Antibody

• Background:

  ING5 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway. [provided by RefSeq].

• NCBI Gene ID:

  84289

• Swiss Prot:

  Q8WYH8

• Accession Number:

  Q8WYH8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ING5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the Central region of human ING5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  28 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ING5

• NCBI Official Name:

  Inhibitor of growth protein 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ullah, M., et al. Mol. Cell. Biol. 28 (22) :6828-6843 (2008)

• Background Reference 02:

  Champagne, K.S., et al. Proteins 72 (4) :1371-1376 (2008)

• Background Reference 03:

  Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

• Other Product Names:

  Inhibitor of growth protein 5, p28ING5, ING5

• Tested Applications:

  WB

• Protein ID:

  57012960

• Physical Properties:

  Liquid