ING1 Antibody

CAT: 0223-30-622Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-30-622Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
NCBI Gene ID
3621
Swiss Prot
Q5T9H0
Accession Number
NP_937862
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ING1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cancer, Apoptosis
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ING1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
32 kDa
Applications Notes
ING1 antibody can be used for detection of ING1 by ELISA at 1:62500. ING1 antibody can be used for detection of ING1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ING1
NCBI Official Name
Inhibitor of growth family, member 1
NCBI Organism
Homo sapiens
Background Reference 01
Ahmed, I.A., (2008) Colorectal Dis 10 (4), 344-351.
Other Product Names
ING1, p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a
Tested Applications
ELISA, WB
Protein ID
38201667
Physical Properties
Liquid

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