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PNPO Antibody

CAT: 0223-63-923Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-923Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.
NCBI Gene ID
55163
Swiss Prot
Q9NVS9
Accession Number
Q9NVS9
Host
Rabbit
Reactivity
Human
Immunogen
This PNPO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the C-terminal region of human PNPO.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
30 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PNPO
NCBI Official Name
Pyridoxine-5'-phosphate oxidase
NCBI Organism
Homo sapiens
Background Reference 01
Musayev, F.N., et al. J. Biol. Chem. 284 (45) :30949-30956 (2009)
Background Reference 02
Khayat, M., et al. Mol. Genet. Metab. 94 (4) :431-434 (2008)
Background Reference 03
Song, H., et al. Schizophr. Res. 97 (1-3), 264-270 (2007) :
Background Reference 04
Mills, P.B., et al. Hum. Mol. Genet. 14 (8) :1077-1086 (2005)
Other Product Names
Pyridoxine-5'-phosphate oxidase, Pyridoxamine-phosphate oxidase, PNPO
Tested Applications
WB
Protein ID
37082126
Physical Properties
Liquid

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