FMOD Antibody

• Background:

  Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.

• NCBI Gene ID:

  2331

• Swiss Prot:

  Q06828

• Accession Number:

  Q06828

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This FMOD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-364 amino acids from the C-terminal region of human FMOD.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  FMOD

• NCBI Official Name:

  Fibromodulin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ehret, G.B., et.al, Eur. J. Hum. Genet. 17 (12), 1650-1657 (2009)

• Background Reference 02:

  Tillgren, V., et.al, J. Biol. Chem. 284 (42), 28543-28553 (2009)

• Other Product Names:

  Fibromodulin, FM, Collagen-binding 59 kDa protein, Keratan sulfate proteoglycan fibromodulin, KSPG fibromodulin, FMOD, FM, SLRR2E

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  223590208

• Physical Properties:

  Liquid