MPP6 Antibody

• Background:

  Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily.

• NCBI Gene ID:

  51678

• Swiss Prot:

  Q9NZW5

• Accession Number:

  Q9NZW5

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This MPP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-388 amino acids from the Central region of human MPP6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  61 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MPP6

• NCBI Official Name:

  MAGUK p55 subfamily member 6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Scheel, A.K., et.al., Ann. Rheum. Dis. 65 (5), 595-600 (2006)

• Background Reference 02:

  Rush, J., et.al., Nat. Biotechnol. 23 (1), 94-101 (2005)

• Background Reference 03:

  Rush, J., et.al., Nat. Biotechnol. 23 (1), 94-101 (2005)

• Other Product Names:

  MAGUK p55 subfamily member 6, Veli-associated MAGUK 1, VAM-1, MPP6, VAM1

• Tested Applications:

  WB, Flow

• Protein ID:

  42560556

• Physical Properties:

  Liquid