MPP3 Antibody

• Background:

  This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs) . MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein.

• NCBI Gene ID:

  4356

• Swiss Prot:

  Q13368

• Accession Number:

  Q13368

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MPP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 406-434 amino acids from the C-terminal region of human MPP3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  66 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MPP3

• NCBI Official Name:

  MAGUK p55 subfamily member 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Qin, L., et al. Zhonghua Gan Zang Bing Za Zhi 15 (7) :509-512 (2007)

• Background Reference 02:

  Kantardzhieva, A., et al. FEBS J. 273 (6) :1152-1165 (2006)

• Background Reference 03:

  Stelzl, U., et al. Cell 122 (6) :957-968 (2005)

• Background Reference 04:

  Fukuhara, H., et al. Oncogene 22 (40) :6160-6165 (2003)

• Other Product Names:

  MAGUK p55 subfamily member 3, Discs large homolog 3, Protein MPP3, MPP3, DLG3

• Tested Applications:

  WB, IF, Flow

• Protein ID:

  150421601

• Physical Properties:

  Liquid