MPP7 Antibody

CAT: 0223-26-765Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-26-765Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MPP7 acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. MPP7 is involved in the assembly of protein complexes at sites of cell-cell contact.Membrane-associated guanylate kinases (MAGUKs) are important adaptor proteins involved in the assembly of protein complexes at sites of cell-cell contact. They are found in synapses, adherens junctions, and tight junctions. All MAGUKs contain at least 1 PDZ domain, an SH3 domain, and a GUK domain, and many contain 1 or 2 L27 domains, which are involved in multimerization of MAGUKs. MPP7 belongs to the p55 stardust subfamily of MAGUKs, which is named for a Drosophila gene required for establishment of cell polarity in the developing fly embryo (Bohl et al., 2007 [PubMed 17237226]) .
NCBI Gene ID
143098
Swiss Prot
Q5T2T1
Accession Number
NP_775767
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MPP7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
HT1080 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MPP7 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
65 kDa
Applications Notes
MPP7 antibody can be used for detection of MPP7 by ELISA at 1:62500. MPP7 antibody can be used for detection of MPP7 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MPP7
NCBI Official Name
Membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
NCBI Organism
Homo sapiens
Background Reference 01
Stucke, V.M., (2007) Mol. Biol. Cell 18 (5), 1744-1755.
Other Product Names
MPP7, FLJ32798, RP11-218D6.5
Tested Applications
ELISA, WB
Protein ID
111154074
Physical Properties
Liquid

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