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MPP1 Antibody

CAT: 0223-55-360Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-360Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
4354
Swiss Prot
Q00013
Accession Number
Q00013
Host
Rabbit
Reactivity
Human
Immunogen
This MPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-327 amino acids from the Central region of human MPP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
52 kDa
Fragment
Rabbit Ig
Symbol
MPP1
NCBI Official Name
55 kDa erythrocyte membrane protein
NCBI Organism
Homo sapiens
Background Reference 01
Seo, P.S., et al. Exp. Biol. Med. (Maywood) 234 (3) :255-262 (2009)
Background Reference 02
Seo, P.S., et al. Biochim. Biophys. Acta 1793 (2) :281-289 (2009)
Background Reference 03
Gosens, I., et al. Hum. Mol. Genet. 16 (16) :1993-2003 (2007)
Background Reference 04
Kusunoki, H., et al. Proteins 64 (3) :804-807 (2006)
Other Product Names
55 kDa erythrocyte membrane protein, p55, Membrane protein, palmitoylated 1, MPP1, DXS552E, EMP55
Tested Applications
WB, IHC-P, Flow
Protein ID
1346575
Physical Properties
Liquid

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