MPP1 Antibody

• Background :

  This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  4354

• Swiss Prot :

  Q00013

• Accession Number :

  Q00013

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This MPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-327 amino acids from the Central region of human MPP1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  52 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  MPP1

• NCBI Official Name :

  55 kDa erythrocyte membrane protein

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Seo, P.S., et al. Exp. Biol. Med. (Maywood) 234 (3) :255-262 (2009)

• Background Reference 02 :

  Seo, P.S., et al. Biochim. Biophys. Acta 1793 (2) :281-289 (2009)

• Background Reference 03 :

  Gosens, I., et al. Hum. Mol. Genet. 16 (16) :1993-2003 (2007)

• Background Reference 04 :

  Kusunoki, H., et al. Proteins 64 (3) :804-807 (2006)

• Other Product Names :

  55 kDa erythrocyte membrane protein, p55, Membrane protein, palmitoylated 1, MPP1, DXS552E, EMP55

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  1346575

• Physical Properties :

  Liquid