CDC20 Antibody

• Background:

  CDC20 is an activating regulatory factor for the APC/C (anaphase promoting complex/cyclosome) . It activates the ubiquitination activity of the APC/C. CDC20 confers a strict destruction-box (D-box) dependence on APC. Levels of CDC20, as well as its binding to APC, peak in mitosis and decrease drastically at early G1.

• NCBI Gene ID:

  991

• Swiss Prot:

  Q12834

• Accession Number:

  Q12834

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CDC20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-84 amino acids from the N-terminal region of human CDC20.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Pig

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  55 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CDC20

• NCBI Official Name:

  Cell division cycle protein 20 homolog

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ge S., et.al., Cell Cycle 8:167-171 (2009) .

• Background Reference 02:

  Gauci S., et.al., Anal. Chem. 81:4493-4501 (2009) .

• Other Product Names:

  Cell division cycle protein 20 homolog, p55CDC, CDC20

• Tested Applications:

  WB, Flow

• Protein ID:

  37537762

• Physical Properties:

  Liquid