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CDC14B Antibody

CAT: 0223-63-773Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-773Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CDC14B is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
NCBI Gene ID
8555
Swiss Prot
O60729
Accession Number
O60729
Host
Rabbit
Reactivity
Human
Immunogen
This CDC14B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-215 amino acids from the Central region of human CDC14B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
57 kDa
Fragment
Rabbit Ig
Symbol
CDC14B
NCBI Official Name
Dual specificity protein phosphatase CDC14B
NCBI Organism
Homo sapiens
Background Reference 01
Bassermann, F., et.al., Cell 134 (2), 256-267 (2008)
Background Reference 02
Rosso, L., et.al., PLoS Biol. (6), E140 (2008)
Other Product Names
Dual specificity protein phosphatase CDC14B, CDC14 cell division cycle 14 homolog B, CDC14B
Tested Applications
WB, Flow
Physical Properties
Liquid

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