Cdc14 Antibody

CAT: 0223-63-472Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-472Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
NCBI Gene ID
8556
Swiss Prot
Q9UNH5
Accession Number
Q9UNH5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Cdc14 antibody is generated from rabbits immunized with a recombinant protein encoding aa 1~379 of human cdc14.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by dialysis against PBS
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
67 kDa
Fragment
Rabbit Ig
Symbol
CDC14A
NCBI Official Name
Dual specificity protein phosphatase CDC14A
NCBI Organism
Homo sapiens
Background Reference 01
Kaiser, B.K., et al. Mol. Biol. Cell 13 (7), 2289-2300 (2002)
Background Reference 02
Mailand, N., et al. Nat. Cell Biol. (4), 317-322 (2002)
Background Reference 03
Bembenek, J. and Yu, H. J. Biol. Chem. 276 (51), 48237-48242 (2001)
Background Reference 04
Li, L., et al. J. Biol. Chem. 275 (4), 2410-2414 (2000)
Other Product Names
Dual specificity protein phosphatase CDC14A, CDC14 cell division cycle 14 homolog A, CDC14A
Tested Applications
WB, IHC-P, Flow
Protein ID
55976620
Physical Properties
Liquid

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