BRD2 Antibody

• Background:

  BRD2 is a mitogen-activated kinase which localizes to the nucleus. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3 but sequence comparison suggests that the protein is not involved in the immune response. Homology to the Drosophila gene female sterile homeotic suggests that this human protein may be part of a signal transduction pathway involved in growth control.

• NCBI Gene ID:

  6046

• Swiss Prot:

  P25440

• Accession Number:

  P25440

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This BRD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-200 amino acids from the Central region of human BRD2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  88 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  BRD2

• NCBI Official Name:

  Bromodomain-containing protein 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Pal, D.K., et al., Am. J. Hum. Genet. 73 (2) :261-270 (2003) .

• Background Reference 02:

  Crowley, T.E., et al., Mol. Endocrinol. 16 (8) :1727-1737 (2002) .

• Background Reference 03:

  Denis, G.V., et al., Cell Growth Differ. 11 (8) :417-424 (2000) .

• Background Reference 04:

  Taniguchi, Y., et al., Genomics 51 (1) :114-123 (1998) .

• Other Product Names:

  Bromodomain-containing protein 2, O2711, Really interesting new gene 3 protein, BRD2, KIAA9001, RING3

• Tested Applications:

  WB, IHC-P

• Protein ID:

  12230989

• Physical Properties:

  Liquid