BRD3 Antibody

• Background:

  This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. BRD3 is ubiquitously expressed in human adult and fetal tissues. BRD3 is markedly expressed in undifferentiated ES cells, whereas the expression was reduced upon endothelial differentiation. BRD3 plays a role in regulation of cell proliferation by allowing cells to enter the proliferative phase of the angiogenic process.BRD3 is also involved in bladder cancer.

• NCBI Gene ID:

  8019

• Swiss Prot:

  Q5T1R6

• Accession Number:

  AAH32124

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BRD3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store BRD3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  61 kDa, 80 kDa

• Applications Notes:

  BRD3 antibody can be used for detection of BRD3 by ELISA at 1:312500. BRD3 antibody can be used for detection of BRD3 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  BRD3

• NCBI Official Name:

  Bromodomain containing 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ishii, H., (2005) DNA Cell Biol. 24 (7), 432-437.

• Other Product Names:

  BRD3, ORFX, RING3L

• Tested Applications:

  ELISA, WB

• Protein ID:

  21594670

• Physical Properties:

  Liquid