BRD4 Antibody

• Background:

  The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t (15;19) (q13; p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.

• NCBI Gene ID:

  23476

• Swiss Prot:

  O60885

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant protein of human BRD4

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Jurkat

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 200kDa

• Fragment:

  IgG

• Symbol:

  BRD4

• Positive Control 2:

  HeLa

• Positive Control 3:

  NIH/3T3

• NCBI Official Name:

  Bromodomain containing 4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  BRD4, CAP, HUNKI, MCAP, HUNK1

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid