BRD7 Antibody

• Background:

  This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  29117

• Swiss Prot:

  Q9NPI1

• Accession Number:

  Q9NPI1

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This BRD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the N-terminal region of human BRD7.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  74 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  BRD7

• NCBI Official Name:

  Bromodomain-containing protein 7

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Burrows, A.E., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (32) :14280-14285 (2010)

• Background Reference 02:

  Drost, J., et al. Nat. Cell Biol. 12 (4) :380-389 (2010)

• Background Reference 03:

  Kikuchi, M., et al. Biochim. Biophys. Acta 1793 (12) :1828-1836 (2009)

• Background Reference 04:

  Kaeser, M.D., et al. J. Biol. Chem. 283 (47) :32254-32263 (2008)

• Other Product Names:

  Bromodomain-containing protein 7, 75 kDa bromodomain protein, Protein CELTIX-1, BRD7, BP75, CELTIX1

• Tested Applications:

  WB

• Protein ID:

  74734307

• Physical Properties:

  Liquid