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BRD7 Antibody

CAT: 0223-57-053Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-053Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
29117
Swiss Prot
Q9NPI1
Accession Number
Q9NPI1
Host
Rabbit
Reactivity
Mouse
Immunogen
This BRD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the N-terminal region of human BRD7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
74 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
BRD7
NCBI Official Name
Bromodomain-containing protein 7
NCBI Organism
Homo sapiens
Background Reference 01
Burrows, A.E., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (32) :14280-14285 (2010)
Background Reference 02
Drost, J., et al. Nat. Cell Biol. 12 (4) :380-389 (2010)
Background Reference 03
Kikuchi, M., et al. Biochim. Biophys. Acta 1793 (12) :1828-1836 (2009)
Background Reference 04
Kaeser, M.D., et al. J. Biol. Chem. 283 (47) :32254-32263 (2008)
Other Product Names
Bromodomain-containing protein 7, 75 kDa bromodomain protein, Protein CELTIX-1, BRD7, BP75, CELTIX1
Tested Applications
WB
Protein ID
74734307
Physical Properties
Liquid

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