BRD7 Antibody

• Background :

  This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID :

  29117

• Swiss Prot :

  Q9NPI1

• Accession Number :

  Q9NPI1

• Host :

  Rabbit

• Reactivity :

  Mouse

• Immunogen :

  This BRD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the N-terminal region of human BRD7.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  74 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  BRD7

• NCBI Official Name :

  Bromodomain-containing protein 7

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Burrows, A.E., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (32) :14280-14285 (2010)

• Background Reference 02 :

  Drost, J., et al. Nat. Cell Biol. 12 (4) :380-389 (2010)

• Background Reference 03 :

  Kikuchi, M., et al. Biochim. Biophys. Acta 1793 (12) :1828-1836 (2009)

• Background Reference 04 :

  Kaeser, M.D., et al. J. Biol. Chem. 283 (47) :32254-32263 (2008)

• Other Product Names :

  Bromodomain-containing protein 7, 75 kDa bromodomain protein, Protein CELTIX-1, BRD7, BP75, CELTIX1

• Tested Applications :

  WB

• Protein ID :

  74734307

• Physical Properties :

  Liquid